NMP Question Set 11 (Pharmacology)

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Course Curriculum
1. Which term describes the time it takes for the plasma concentration of a drug to reduce by half? *
2. What is a prodrug? *
3. Which process primarily occurs in the liver and transforms drugs into more water-soluble compounds? *
4. What does bioavailability refer to? *
5. Which route of administration consistently by-passes the first-pass effect? *
6. What is the volume of distribution (Vd)? *
7. Which statement best defines clearance in pharmacokinetics? *
8. What is the therapeutic index (TI)? *
9. Which term describes the maximum effect a drug can produce? *
10. What does a low therapeutic index indicate? *
11. Which factor can increase the half-life of a drug? *
12. What is the primary site for drug metabolism? *
13. Which process describes the movement of a drug from systemic circulation to tissues? *
14. What is the main route of excretion for most drugs? *
15. Which term refers to the proportion of a drug that is bound to plasma proteins? *
16. What effect does a competitive antagonist have on an agonist's dose-response curve? *
17. Which phase of drug metabolism involves conjugation reactions? *
18. What is the primary goal of drug metabolism? *
19. Which factor does NOT affect drug absorption? *
20. What is the significance of first-pass metabolism? *