NMP Question Set 12 (Pharmacology)

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Course Curriculum
1. Which route of drug administration has 100% bioavailability? *
2. What is the main organ responsible for first-pass metabolism? *
3. Which of the following is a prodrug that requires activation by the liver? *
4. What type of drugs pass easily through the blood-brain barrier? *
5. What effect does enzyme induction have on drug metabolism? *
6. Which of the following is a drug that undergoes enterohepatic recycling? *
7. Which factor most influences the distribution of a lipophilic drug *
8. What is the main protein drugs bind to in plasma? *
9. A beta-2 agonist like salbutamol primarily causes which effect? *
10. Which class of drug binds to receptors but causes no activation? *
11. What is the meaning of 'therapeutic window'? *
12. Which drug characteristic is influenced by the blood flow to the absorption site? *
13. What happens when two drugs compete for plasma protein binding? *
14. What is the primary excretion route for aminoglycosides? *
15. Which enzyme system is most involved in Phase 1 metabolism? *
16. A narrow therapeutic index means: *
17. What is the half-life of a drug? *
18. Which drug inhibits proton pumps in the stomach lining? *
19. Which type of drug binds to a receptor and produces a reduced response *
20. In renal impairment, how might drug dosing be adjusted? *